Looking for Cures

The University of Pittsburgh is making a big push into drug discovery by opening a laboratory that will focus exclusively on treatments for rare diseases, especially some kinds of cancer….
New treatments for a range of similar diseases, including Parkinson’s, Lou Gehrig’s and Alzheimer’s, also may be discovered in the new lab, according to Dr. Steven DeKosky, director of the Alzheimer’s Disease Research Center at Pitt. In this family of medical problems, protein molecules go bad, setting off a cascade of cellular changes that result in neuromuscular problems, including difficult speech and movement, DeKosky said.
The hope is to find compounds whose molecules block the start of the cascade, kind of like finding a key that fits a specific lock, said DeKosky. “It’s a hugely exciting time.”

Read the rest of the article at MSNBC.

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