Structure and Stability of Internodal Myelin in Mouse Models of Hereditary Neuropathy

Journal of Neuropathology & Experimental Neurology. 64(11):976-990, November 2005. Avila, Robin L BS; Inouye, Hideyo PhD; Baek, Rena C BS; Yin, Xinghua MD; Trapp, Bruce D PhD; Feltri, M Laura MD; Wrabetz, Lawrence MD; Kirschner, Daniel A PhD Peripheral neuropathies Continue reading Structure and Stability of Internodal Myelin in Mouse Models of Hereditary Neuropathy

Curcumin Treatment Abrogates Endoplasmic Reticulum Retention and Aggregation-Induced Apoptosis Associated with Neuropathy-Causing Myelin Protein Zero-Truncating Mutants

Mehrdad Khajavi, Ken Inoue, Wojciech Wiszniewski, Tomoko Ohyama, G. Jackson Snipes, and James R. Lupski The American Journal of Human Genetics, volume 77 (2005), pages 841–850 Mutations in MPZ, the gene encoding myelin protein zero (MPZ), the major protein constituent Continue reading Curcumin Treatment Abrogates Endoplasmic Reticulum Retention and Aggregation-Induced Apoptosis Associated with Neuropathy-Causing Myelin Protein Zero-Truncating Mutants

Booklet is ready and more news from HNF – October 2005

The following is from the Hereditary Neuropathy Foundation‘s October newsletter: We’re pleased to announce that our patient information booklet is now available for distribution to our registered HNF members. This high-quality production presents an in depth overview of the common Continue reading Booklet is ready and more news from HNF – October 2005

Researchers Find Protein Determines Nerve’s Fate

Researchers at the Skirball Institute of Biomolecular Medicine, New York University (NYU) School of Medicine, have found that a protein (neuregulin-1 type III, or NRG1-III) essential for the protective wrapping around a nerve’s central wiring, or axons, also determines its Continue reading Researchers Find Protein Determines Nerve’s Fate

Local anesthetics are effective for neuropathic pain

Lidocaine and similar local anesthetics are effective for treating pain that emanates from damaged nerves, according to a systematic review of current evidence. Neuropathic pain, which can occur with chronic diseases or conditions, is frequently unresponsive to treatment and worsens Continue reading Local anesthetics are effective for neuropathic pain