One big step for Geron: Therapy that enabled paralyzed rats to walk ready for test on humans, stem-cell firm says

(Editor’s note: This will have implications for Dejerine-Sottas research in the future:) Using human embryonic stem cells, the Menlo Park company has developed a therapy that enables paralyzed rats to walk and that it claims shows no dangerous side effects Continue reading One big step for Geron: Therapy that enabled paralyzed rats to walk ready for test on humans, stem-cell firm says

The neuropathic pain triad: neurons, immune cells and glia

Nat Neurosci. 2007 Nov;10(11):1361-8. Scholz J, Woolf CJ. Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA. Nociceptive pain results from the detection of intense or noxious stimuli Continue reading The neuropathic pain triad: neurons, immune cells and glia

Developmental loss of NT-3 in vivo results in reduced levels of myelin-specific proteins

Glia. 2008 Feb;56(3):306-17. Developmental loss of NT-3 in vivo results in reduced levels of myelin-specific proteins, a reduced extent of myelination and increased apoptosis of Schwann cells. Woolley AG, Tait KJ, Hurren BJ, Fisher L, Sheard PW, Duxson MJ. Department Continue reading Developmental loss of NT-3 in vivo results in reduced levels of myelin-specific proteins