NT3 Gene Therapy for CMT1A Benefits Mice

From MDA’s Quest magazine: Mice with a disorder resembling type 1A Charcot-Marie-Tooth (CMT1A) disease that received a single intramuscular injection of genes for the protein neurotrophin 3 (NT3) showed improvements in grip strength, ability to stay on a rotating rod, Continue reading NT3 Gene Therapy for CMT1A Benefits Mice

Developmental loss of NT-3 in vivo results in reduced levels of myelin-specific proteins

Glia. 2008 Feb;56(3):306-17. Developmental loss of NT-3 in vivo results in reduced levels of myelin-specific proteins, a reduced extent of myelination and increased apoptosis of Schwann cells. Woolley AG, Tait KJ, Hurren BJ, Fisher L, Sheard PW, Duxson MJ. Department Continue reading Developmental loss of NT-3 in vivo results in reduced levels of myelin-specific proteins

Bone Marrow Cell Transplants Help Nerve Regeneration

ScienceDaily (Dec. 5, 2007) — A study carried out by researchers at the Kyoto University School of Medicine has shown that when transplanted bone marrow cells (BMCs) containing adult stem cells are protected by a 15mm silicon tube and nourished Continue reading Bone Marrow Cell Transplants Help Nerve Regeneration

New Roles For Growth Factors: Enticing Nerve Cells To Muscles

During embryonic development, nerve cells hesitantly extend tentacle-like protrusions called axons that sniff their way through a labyrinth of attractive and repulsive chemical cues that guide them to their target. While several recent studies discovered molecules that repel motor neuron Continue reading New Roles For Growth Factors: Enticing Nerve Cells To Muscles