Clinical Trials

StatusStudy nameSponsorStudy typeLimited to subtypes
RecruitingCharcot-Marie-Tooth Disease (CMT) Infant Scale (INC-6611)Sydney Childrens' NetworkObservationalCharcot-Marie-Tooth Disease (CMT)
RecruitingAssessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1ASponsor:
Pharnext SA
Collaborators:
SynteractHCR
INC Research
Information provided by (Responsible Party):
Pharnext SA
Intervention: Drug: PXT3003Charcot-Marie-Tooth Disease Type 1A
RecruitingGenetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2University of IowaObservationalConditions: Charcot-Marie-Tooth Disease, Type Ia (Disorder); HMSN, CMT2
RecruitingNatural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and OthersUniversity of IowaObservationalCharcot-Marie-Tooth
Not Yet RecruitingBALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth DiseaseUniversity College London HospitalsBehavioral: Falls management plus exercise training; Behavioral: Falls management onlyCharcot-Marie-Tooth Disease, Type IA
Unknown; recruiting deadline passed; status has not been verified in more than 2 years.Correlation Between Clinical and Electrophysiological Phenotypes in a Population of Patients With Neuropathy Charcot-Marie-Tooth Disease Type 1AUniversity Hospital, Clermont-Ferrand ObservationalCharcot-Marie-Tooth Type 1A Neuropathy
RecruitingDevelopment of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMTUniversity of IowaObservationalCharcot-Marie-Tooth
CompletedMexiletine for Muscle Cramps in Charcot Marie Tooth DiseaseUniversity of RochesterDrugs: Mexiletine, placeboCharcot-Marie-Tooth
UnknownTreadmill, Stretching and Proprioceptive Exercise (TreSPE) Rehabilitation Program for Charcot?Marie?Tooth Neuropathy Type 1A (CMT1A)University of GenovaInterventions: Other: TreSPE; Other: SPECharcot-Marie-Tooth Disease; Charcot-Marie-Tooth Disease Type 1A
Not Yet RecruitingTools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and BiomarkersAssistance Publique Hopitaux De MarseilleInterventions: Other: Clinical evaluation; Other: electrophysiological record; Other: Muscle MRI; Other: blood samples analysisCharcot-Marie-Tooth Disease Type 1A
CompletedAn Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) PatientsUniversity of South FloridaObservationalCharcot Marie Tooth Disease (CMT); Hereditary Sensory and Motor Neuropathy; Nerve Compression Syndromes; Tooth Diseases; Congenital Abnormalities; Genetic Diseases, Inborn; Heredodegenerative Disorders, Nervous System
CompletedAscorbic Acid Treatment in CMT1A Trial (AATIC)Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Drug: ascorbic acidCharcot-Marie-Tooth Disease; Hereditary Motor and Sensory Neuropathies
Completed; has resultsPhase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1APharnext SAInterventions: Drug: PXT3003 Low dose; Drug: PXT3003 Intermediate Dose; Drug: PXT3003 High Dose; Other: PlaceboCharcot-Marie-Tooth Disease; Hereditary Neuropathy With Liability to Pressure Palsies; Genetic Disorders; Tooth Disorders
RecruitingDisability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS) (DSI and HMSN)University of IowaObservationalCharcot Marie Tooth Disease
Inherited Peripheral Neuropathy
CompletedSurvey of Current Management of Orthopaedic Complications in CMT PatientsUniversity College London HospitalsSurveyCharcot-Marie-Tooth Disease
Not Yet RecruitingUlipristal Acetate In Disease Charcot-Marie-Tooth Type of 1AUniversity Hospital, Strasbourg, France Drug: EllaOne; Drug: EllaOne placeboCMT1A
Active, not recruitingPhase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT)Pharnext SADrug: PXT3003 dose 1; Drug: PXT3003 dose 2; Drug: placeboCharcot-Marie-Tooth Disease Type 1A
CompletedDevelopment and Validation of a Disability Severity Index for CMTUniversity of Iowa ObservationCharcot Marie Tooth Disease
CompletedNociceptive Processing in Acute Cutaneous Nerve Entrapment SyndromeRadboud UniversityObservation, Quantitative Sensory Testing analysisACNES patients
Patients being treated in past for anterior cutaneous nerve entrapment syndrome
CompletedHigh Dose Ascorbic Acid Treatment of CMT1AWayne State UniversityDrug: Ascorbic acid (Vitamin C); Drug: placeboCharcot-Marie-Tooth Disease, Type Ia
CompletedFollow up and Observation of Charcot Marie Tooth Disease in FamiliesHadassah Medical OrganizationObservationCharcot-Marie-Tooth Disease
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years. Evaluation of the Analgesic Efficiency of the Transcutaneous Neurostimulation in the Charcot Syndrome Marie Tooth on the Pains of Lower LimbsCentre Hospitalier Universitaire de Nice TENS deviceCharcot-Marie-Tooth
CompletedPatient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited NeuropathiesUniversity of South FloridaWeb-based surveyCarpal Tunnel Syndrome; Charcot-Marie-Tooth Disease; Inherited Peripheral Neuropathy
CompletedDriving Ability in Patients With CMT 1AJerath U Nivedita, University of IowaDevice: UIHC Driving SimulatorCMT 1A
RecruitingSERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot StudyMedDay Pharmaceuticals SA Drug: MD1003Chronic Inflammatory Demyelinating Polyneuropathy; Peripheral Neuropathy; Charcot-Marie-Tooth Disease; Charcot-Marie-Tooth Disease Type 1A; Charcot-Marie-Tooth Disease, Type IA
CompletedStudy of Electrical Impedance Myography (EIM) in ALSSkulpt, Inc. Device: Electrical impedance myography (EIM)Amyotrophic Lateral Sclerosis; Motor Neuron Disease; Charcot-Marie-Tooth Disease; Multiple Sclerosis
RecruitingGenetics of Pediatric-Onset Motor Neuron and Neuromuscular DiseasesNemours Children's Clinic sample collectionSpinal Muscular Atrophy; Charcot-Marie-Tooth Disease; Muscular Dystrophy; Spinal Muscular Atrophy With Respiratory Distress 1; Amyotrophic Lateral Sclerosis; Motor Neuron Disease; Neuromuscular Disease; Peroneal Muscular Atrophy; Fragile X Syndrome
CompletedCentralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological DiseasesUniversity at Buffalo ObservationalClinically Isolated Syndrome (CIS); Multiple Sclerosis (MS); Other Neurological Disorders (OND); Healthy (HC)
Not Yet RecruitingMusculoskeletal Pathologies of the Upper Extremity in Surgical Device MechanicsDistrict Hospital, TuttlingenOther: Clinical examination and data processing of questionnairesMusculoskeletal Diseases or Conditions
RecruitingGenetic and Physical Study of Childhood Nerve and Muscle DisordersNational Institute of Neurological Disorders and Stroke (NINDS) Screening, sample collection, and observation of patients and family members.Muscular Dystrophies; Muscle Myopathies; Hereditary Spastic Paraplegias; Inherited Neuropathies; Inherited Neuromuscular Conditions